Study finds 10 predictors linked to opioid overdose in chronic pain patients

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octobre 23, 2023

A McMaster University study found the risk of fatal and non-fatal opioid overdose after prescription increased up to sixfold in cases involving predictors such as a high dose of medication, depression or pancreatitis. Other predictors strongly associated with opioid overdose include:

  • Use of multiple pharmacies;
  • Multiple opioid prescribers;
  • Fentanyl prescription;
  • Current substance use disorder;
  • Bipolar disorder;
  • Other mental illness; and
  • History of opioid overdose.

Researchers hope the predictors will create collaborative decision-making between doctors and their patients when it comes to prescribing opioids for chronic pain. Around 7.6 million people in Canada live with chronic pain.

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